Don Bosco Technical College (DBTC or Don Bosco Mandaluyong) is a private Catholic educational institution in Manila, Philippines, owned and operated by the Salesians of Don Bosco. Don Bosco Mandaluyong offers all-boys elementary education, all-boys secondary education, co-educational tertiary education, night school (alternative learning system), and vocational training for out-of-school male youth. The college department was formerly exclusive for males until 2004, when the department made history by accepting female students. Established in 1953, it is the first Don Bosco educational institution in Metro Manila.

It is part of the IUS or the Istituzioni Universitarie Salesiane (Salesian University Institutions), the Don Bosco Educational Apostolate of the Philippines and the Don Bosco Philippines North Province (DB-FIN). Don Bosco Mandaluyong was awarded the ISO 9001:2000 certification (Certificate No. 6720) by Moody International Certification (Malaysia) Sdn. Bhd. and United Kingdom Accreditation Service.

Don Bosco Mandaluyong is envisaged as one of the "big three" schools in Mandaluyong City, together with La Salle Green Hills and Lourdes School of Mandaluyong, which also offer all-boys elementary and secondary education. DBTC is deemed as the "motherhouse of all Salesian works in the Philippines," making it the premier Salesian institution for higher learning in the country.^[1] Its campus is located at 736 General Kalentong Street in Mandaluyong City, Metro Manila, Philippines.